Steroid induced osteoporosis symptoms

In a performance setting, Cytomel doses will be very similar to hypothyroidism treatment plans. The individual will normally begin with 25mcg per day and increase the total dose -25mcg every 2-4 weeks as needed. Most will find they will have no need to go above 75-100mcg per day, with the 125mcg per day range being acceptable for very short periods of time. Such a high dose might be acceptable at the end of a harsh contest diet but should not be a regular dose through the brunt of the diet. As for total use, 6-8 weeks will be the safest total duration. Longer can be acceptable, such as 8-12 weeks, but it does increase the risk of thyroid dependency. However, most healthy adults should not have an issue. Once you have reached your high end dose and it’s time to come off, you are encouraged to drop the dose down to 25mcg per day and hold at that dose for 7-10 days. This will allow the body to adjust and protect you from falling into hypothyroidism. For no reason should you discontinue use abruptly, the 7-10 day low dose is imperative.

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Because steroids are lipophilic, they diffuse easily through the cell membranes, and therefore have a very large distribution volume. In their target tissues, steroids are concentrated by an uptake mechanism which relies on their binding to intracellular proteins (or " receptors ", see below). High concentration of steroids are also found in adipose tissue, although this is not a target for hormone action. In the human male, adipose tissue contains aromatase activity, and seems to be the main source of androgen-derived estrogens found in the circulation. But most of the peripheral metabolism occurs in the liver and to some extent in the kidneys, which are the major sites of hormone inactivation and elimination, or catabolism (see below).

Steroid induced osteoporosis symptoms

steroid induced osteoporosis symptoms

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