Side effects of high dose steroid therapy

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Hydralazine (Apresoline) is an antihypertensive medication used to treat high blood pressure . It is a peripheral arterial vasodilator and causes relaxation of blood vessels which carry blood away from the heart and towards the organs and tissues. The exact mechanism of how hydralazine causes arterial smooth muscle relaxation is not yet understood. Hydrazine affects calcium movement within blood vessels. Calcium is required for muscle contraction and therefore disturbances in calcium movement may cause smooth muscle relaxation in the blood vessels. Hydralazine is selective for arterioles (small arteries), and the overall effects of treatment include a decrease in arterial blood pressure , and peripheral vascular resistance.

Dizziness, lightheadedness or fainting (all types of antihypertensive medications but especially alpha blockers). When standing up from a seated position, rise slowly . When getting up from a recumbent position, sit on the edge of the bed with your feet dangling for one to two minutes and then stand up slowly. Be especially careful about rising slowly when getting up in the middle of the night to use the bathroom. Don't overexert yourself during exercise or in hot weather. Also, try to avoid standing for long periods of time and consuming large amounts of alcohol.

Side effects of high dose steroid therapy

side effects of high dose steroid therapy

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