Oxymetholone synthesis

The question of product integrity is always central in the minds of BM customers, “Can I purchase safe products from this source?” The virtually anonymity of internet sites coupled with traditionally high provider turnover rates has made answering this question even harder in today’s society. The BM is filled with “scammers”, individuals who simply set up shop to dupe customers out of money with no plan or intention of delivering on the promised AAS. These are actually the good guys, those who promote the once bitten syndrome and scare many would-be buyers/users away from further attempts at steroids. At least they have the decency (used lightly) to take your money and run. Numerous dealers run repackaging scams in which very cheap steroids are placed in expensive product labeling and sold at a premium. These less expensive forms of AAS produce greater side effects, which can be particularly dangerous to women who think they are buying a very mild steroid only to receive a significantly harsher product. Still others produce imposter or fake steroids, which are often bottles of vegetable oils labeled to look like AAS. Along the same lines are those manufactured under conditions that are far less sanitary than required by the FDA. All of the above hazards can lead to health problems ranging from minor such as abscesses and infections, to major like severe illness and death.

As we discussed above, Dianabol carries a strong aromatizing nature, and is a C17-aa anabolic steroid; as such, its side-effects will revolve around these factors. As an aromatizing steroid, this means there can be a testosterone to estrogen conversion, and if estrogen levels go to high it can lead to some complications. When estrogen levels increase, the hormone can attach to the receptors and cause gynecomastia (male-breast enlargement) and it can also promote excess water retention and high blood pressure; Dbol is notorious for promoting high blood pressure. Needless to say, if you already suffer from high blood pressure you should not touch this steroid, but if it's healthy you'll need to ensure it stays this way. For this reason, in-order to combat and avoid these estrogenic side-effects of Dbol, the use of an Aromatase Inhibitor (AI) is often advised. It shouldn't be too hard to see how this can help; after all, an AI inhibits aromatase, but it goes a step further by reducing the body's total estrogen levels. Of course, and this cannot be overstressed, you must keep your doses at a responsible level; most will need at least 20mg per day for any anabolic promotion, with a maximum dosing of 50mg per day. It should be noted; if you've never used this steroid before, you should not start with a high end dose; start low and see how you respond.

Despite all positive effects of doping on the body they could be dangerous. Possible side effects of anabolic steroids can be avoided by choosing the right form (oral or injectable) and combination as well as by taking reasonable androgenic dosages. It has to be mentioned, that the most side effects of drugs disappear after the cycle is completed. Moreover, many of them can be blocked during the cycle by using respective supplements. Therefore, in order to avoid possible negative consequences one shall pay attention to studying information about the drugs prior to use them.

Flutamide acts as a selective, competitive , silent antagonist of the androgen receptor (AR). [1] Its active metabolite , 2-hydroxyflutamide , has between 10- to 25-fold higher affinity for the AR than does flutamide, and hence is a more powerful antiandrogen in comparison. [1] [21] [46] [47] However, at high concentrations, unlike flutamide, 2-hydroxyflutamide is able to weakly activate the AR. [1] [48] Flutamide has far lower affinity for the AR than do steroidal antiandrogens like spironolactone and cyproterone acetate, and it is a relatively weak antiandrogen in terms of potency by weight, but the large dosages at which flutamide is used appear to compensate for this. [49] In accordance with its selectivity for the AR, flutamide possesses no progestogenic , (direct) estrogenic , glucocorticoid , or antigonadotropic activity. [25] [50] Similarly to nilutamide, bicalutamide, and enzalutamide , flutamide crosses the blood-brain-barrier and exerts central antiandrogen actions. [51]

Oxymetholone synthesis

oxymetholone synthesis

Flutamide acts as a selective, competitive , silent antagonist of the androgen receptor (AR). [1] Its active metabolite , 2-hydroxyflutamide , has between 10- to 25-fold higher affinity for the AR than does flutamide, and hence is a more powerful antiandrogen in comparison. [1] [21] [46] [47] However, at high concentrations, unlike flutamide, 2-hydroxyflutamide is able to weakly activate the AR. [1] [48] Flutamide has far lower affinity for the AR than do steroidal antiandrogens like spironolactone and cyproterone acetate, and it is a relatively weak antiandrogen in terms of potency by weight, but the large dosages at which flutamide is used appear to compensate for this. [49] In accordance with its selectivity for the AR, flutamide possesses no progestogenic , (direct) estrogenic , glucocorticoid , or antigonadotropic activity. [25] [50] Similarly to nilutamide, bicalutamide, and enzalutamide , flutamide crosses the blood-brain-barrier and exerts central antiandrogen actions. [51]

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