This data was collected primarily throughout the month of December 2016. We tallied each individual’s score, then arranged the list from highest to lowest and used our qualitative judgment (. the Greatist editorial staff had a good old-fashioned debate) to fill in the gaps. We purposefully excluded most health care executives, professional athletes, and spiritual leaders, unless we felt they strongly contributed to health, fitness, or mental health. If you think anyone is missing, please reach out to us on Twitter , Facebook , or Instagram .
Watch stress . Corticotropin-releasing hormone (CRH) stimulates mast cells to release histamine . But CRH also releases cortisol , which inhibits histamine secretion. In normal circumstances, with acute, short-lived stress, this works to oppose excessive histamine. In chronic stress, things change. We become resistant to stress hormones , and cortisol loses a bit of its histamine-inhibiting luster. We’re releasing massive amounts of histamine-stimulating CRH, but the cortisol is unable to stem the tide. So: watch stress. Avoid it, limit it, mitigate it , or rethink it . And consider an effective adaptogen/herbal supplement to get yourself over the hump when you need it. (I swear by this one .)